Nitrofurantoin-induced acute pulmonary toxicity

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Nitrofurantoin‐induced acute pulmonary toxicity

We report a case of a female admitted to the emergency department with fever and severe type I acute respiratory failure. After detailed examination, all other potential causes were excluded and the patient was diagnosed with nitrofurantoin-induced acute pulmonary toxicity.

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Fatal Nitrofurantoin-Induced Pulmonary Toxicity: A Potentially Preventable Medical Error

The majority of patients affected with nitrofurantoin pulmonary toxicity are elderly women [1]. The proposed mechanism of toxicity is either idiosyncratic oxydant-mediated tissue injury by nitrofurantoin metabolites causing depletion of cellular glutathione (chronic form) or by immunological response induced by nitrofurantoin metabolites acting as heptanes and resulting a hypersensitivity react...

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Acute pulmonary reaction to nitrofurantoin.

Pinerua, R. F. and Hartnett, B. J. S. (1974). Thorax, 29, 599-602. Acute pulmonary reaction to nitrofurantoin. Acute pulmonary reaction to nitrofurantoin is a rare complication of a commonly used drug. This report of such a reaction presents studies of pulmonary function more detailed than are so far available. Studies made nine days after the drug had been withdrawn showed arterial hypoxaemia ...

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Nitrofurantoin-induced pulmonary fibrosis: a case report

INTRODUCTION Nitrofurantoin is a commonly used drug in the treatment and prevention of urinary tract infections. Many adverse effects of nitrofurantoin have been documented, including aplastic anemia, polyneuritis, and liver and pulmonary toxicity. CASE PRESENTATION We describe the clinical history and the autopsy findings in a 51-year-old woman with lung fibrosis of unknown etiology. She had...

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Nitrofurantoin-induced pulmonary toxicity: A case report and review of the literature.

This paper describes a case of lung injury attributed to the use of Nitrofurantoin and a review of the relevant literature. An 88-year-old woman was admitted to the floor for the evaluation of recent symptoms of dyspnea, fatigue and productive cough. She was initiated on nitrofurantoin 300 mg per day for the treatment of a urinary tract infection 3 days earlier. Upon examination, chest ausculta...

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ژورنال

عنوان ژورنال: Respirology Case Reports

سال: 2016

ISSN: 2051-3380

DOI: 10.1002/rcr2.131